Prognostic significance of various biochemical parameters in acute organophosphorus poisoning
نویسندگان
چکیده
منابع مشابه
Organophosphorus poisoning (acute).
INTRODUCTION Acetylcholinesterase inhibition by organophosphorus pesticides or organophosphate nerve agents can cause acute parasympathetic system dysfunction, muscle weakness, seizures, coma, and respiratory failure. Prognosis depends on the dose and relative toxicity of the specific compound, as well as pharmacokinetic factors. METHODS AND OUTCOMES We conducted a systematic review and aimed...
متن کاملIndependent Prognostic Factors for Acute Organophosphorus Pesticide Poisoning.
BACKGROUND Acute organophosphorus pesticide poisoning (AOPP) is becoming a significant problem and a potential cause of human mortality because of the abuse of organophosphate compounds. This study aims to determine the independent prognostic factors of AOPP by using multivariate logistic regression analysis. METHODS The clinical data for 71 subjects with AOPP admitted to our hospital were re...
متن کاملAcute organophosphorus insecticide poisoning in Sri Lanka.
Records of 92 cases of acute organophosphorus (OP) insecticide poisoning were analysed. Of the patients 91% were under 30 years of age and 86% were males. The common agents were Dimethoate, Methamidophos, Malathion, Monocrotophos and Fenthion. Poisoning was due to ingestion with suicidal intent in the majority. In addition to the acute cholinergic features, the other important manifestations we...
متن کاملManagement of acute organophosphorus pesticide poisoning
Organophosphorus pesticide self-poisoning is an important clinical problem in rural regions of the developing world, and kills an estimated 200,000 people every year. Unintentional poisoning kills far fewer people but is a problem in places where highly toxic organophosphorus pesticides are available. Medical management is difficult, with case fatality generally more than 15%. We describe the l...
متن کاملZebrafish Models for Human Acute Organophosphorus Poisoning
Terrorist use of organophosphorus-based nerve agents and toxic industrial chemicals against civilian populations constitutes a real threat, as demonstrated by the terrorist attacks in Japan in the 1990 s or, even more recently, in the Syrian civil war. Thus, development of more effective countermeasures against acute organophosphorus poisoning is urgently needed. Here, we have generated and val...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicology International
سال: 2014
ISSN: 0971-6580
DOI: 10.4103/0971-6580.139800